Glucosamine
Glucosamine is an aminosugar. It is made in the body from
the simple carbohydrate glucose (sugar) and the amino acid glutamine.
Although our bodies generally use glucose to produce energy, the
aminosugars found in glucosamine are incorporated into the structure of
body tissue. Glucosamine is involved in the formation of cartilage, nails,
tendons, skin, eyes, bones, ligaments, and heart valves. It also plays a
role in the mucous secretions of the digestive, respiratory, and urinary
tracts. Of particular interest is its role in cartilage.
Cartilage is connective tissue at the ends of bones
(where it is known as articular cartilage). It separates bones so that
they do not grind together, causing stiffness and pain. Cartilage also
serves as a shock absorber. Briefly put, cartilage protects our bones from
the wear and tear of movement.
One way to think of cartilage is as a super sponge. It
soaks up water (more accurately, synovial fluid) when a joint is at rest,
and squeezes out the water when a joint moves. As the joint rests again,
it again soaks up water. This spongelike effect of cartilage makes it a
shock absorber, buffering our bones and body from the wear and tear of
making thousands of movements per day. Cartilage is also slipperyfive to
eight times more slippery than ice. Thus, when two bones do meet, the
cartilage at the ends of each bone allows them to slide off each other,
adding to the buffering effect.
The Role of glucosamine
Glucosamine stimulates chondrocytes to produce more
collagen and proteoglycans. The more glucosamine there is, the more
collagen and proteoglycans there are, and the more water can be absorbed.
The end result is healthier cartilage. Because of these properties,
glucosamine can help the body help itself repair damaged or eroded
cartilage. It works at the cellular level to reinforce our natural
"repair" ability.
Glucosamine
Both glucosamine sulfate and glucosamine HCL are forms of
glucosamine. Glucosamine makes up 63 percent of glucosamine sulfate and 83
percent of glucosamine HCL. Most human studies have used glucosamine
sulfate. This is because the company that paid for the research developed
this form. Glucosamine HCL has not been evaluated as extensively, but
clinical experience from a variety of health practitioners indicates that
glucosamine HCL works just as well. Many health practitioners recommend
trying one, and if that does not work, trying the other.
Frame
Essentials
gives you both of these at once.
When things go wrong
As we age, the millions of movements we have made in our
lives begin to wear and tear on cartilage. Catilage begins to deteriorate,
and our bones begin to rub together. This becomes noticeable around age
45, and often happens in the fingers, knees, hips, neck, and lower back.
Cartilage can also be destroyed through trauma, injury, and repetitive
actions.
What to do
One way to counter the deterioration and destruction of
cartilage is to increase the amount of glucosamine your body hasremember,
glucosamine helps the body build and repair damaged cartilage. Glucosamine
is not only a "builder" but also a painkiller. In sum, it
improves joint function and reduces pain. It makes no difference whether
it comes from foods we eat or from supplements.